I-Tetrabutylammonium iodideiyi-reagent esetshenziswa kabanzi ekuphenduleni kwamakhemikhali okuhlukahlukene.Enye yezinhlelo zokusebenza ezithakazelisa kakhulu futhi ezifundwa kabanzi ze-TBAI ukusetshenziswa kwayo ekuhlanganiseni ama-azides.
Igama elifanayo:I-TBAI
Inombolo ye-CAS:311-28-4
Izakhiwo
I-Chemical Formula
C16H36IN
Isisindo samangqamuzana
369.37g/mol
Izinga Lokushisa Lokugcina
I-Melting Point
141-143 ℃
Ubumsulwa
≥98%
Ingaphandle
i-crystal emhlophe noma i-powder emhlophe
I-Tetrabutylammonium iodide, eyaziwa nangokuthi i-TBAI, iyi-reagent esetshenziswa kabanzi ekuphenduleni kwamakhemikhali okuhlukahlukene.Enye yezinhlelo zokusebenza ezithakazelisa kakhulu futhi ezifundwa kabanzi ze-TBAI ukusetshenziswa kwayo ekuhlanganiseni ama-azides.Kodwa iyiphi indlela ebangela le mpendulo, futhi i-TBAI inegalelo kanjani kuyo?
Indlela yokusabela ye-TBAI iyinkimbinkimbi futhi ihlanganisa izinyathelo ezimbalwa ezibalulekile.Ngokuvamile, lokhu kusabela kuhilela isizukulwane se-in situ se-hypoiodite esivela ku-TBAI kanye ne-co-reactant eyaziwa ngokuthi i-TBHP.Le hypoiodite ibe isisabela nenhlanganisela ye-carbonyl ukuze yakhe okuphakathi okuba yi-azide.Ekugcineni, i-hypoiodite ivuselelwa kabusha nge-oxidation.
Isinyathelo sokuqala endleleni yokusabela sihilela ukukhiqizwa kwe-hypoiodite kusuka ku-TBAI ne-TBHP.Lesi yisinyathelo esibalulekile ngoba siqala ukusabela ngokuhlinzeka ngezinhlobo ze-iodine ezidingekayo ukuze kufakwe i-carbonyl oxidation elandelayo.I-Hypoiodate iyasebenza kakhulu futhi iyakwazi ukukhuthaza ukusabela kwamakhemikhali okuningi okuhlukahlukene, okuhlanganisa i-halogenation kanye ne-oxidation.
Uma i-hypoiodite yakhiwe, ihlangana nenhlanganisela ye-carbonyl yakhe okuphakathi.Lokhu okuphakathi kuyabe sekwenziwa kusetshenziswa i-reagent ye-imide, enezela ama-athomu amabili e-nitrogen ku-molecule futhi empeleni "iyenze isebenze" ukuze iqhubeke nokusabela.Kuleli qophelo, i-TBAI iyifeze injongo yayo futhi ayisadingeki ekuphenduleni.
Isinyathelo sokugcina kumshini sibandakanya ukuvuselelwa kwe-hypoiodite.Lokhu kufezwa nge-oxidation kusetshenziswa ama-co-reactants njenge-hydrogen peroxide.Ukuvuselela i-hypoiodite kubalulekile ngoba kuvumela ukusabela ukuthi uqhubeke nokuhamba ngebhayisikili futhi ukhiqize ama-azides amaningi.
Sekukonke, indlela yokuphendula ye-TBAI yinhle kakhulu futhi isebenza kahle.Ngokukhiqiza i-hypoiodite in situ futhi iyisebenzisele ukwenza inhlanganisela ye-carbonyl, i-TBAI ivumela ukukhiqizwa kwama-azides obekungaba nzima noma okungenzeki ukuwahlanganisa.Noma ngabe ungusokhemisi osebenza elabhorethri yocwaningo noma umenzi ofuna ukukhiqiza izinto ezintsha, i-TBAI inokuningi engakunikeza.Izame namuhla!
Isikhathi sokuthumela: Jun-14-2023